Schedule
SUNDAY 28 JUNE
18:30 | 19:30
Opening Lecture
Giuliano Scarcelli (University of Maryland)
Listening to biomechanics: Brillouin microscopy from fundamental physics to clinical insightsei
MONDAY 29 JUNE
09:00 | 09:15
POSTER AREA
–
–
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
Institutional Greetings and Welcome
MEETING ROOM 2
SCIROCCO
Parallel
–
MEETING ROOM 3
LIBECCIO
Parallel
–
09:15 | 10:00
POSTER AREA
–
Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
Plenary
Jennifer Lippincott-Schwartz (Janelia Research Campus)
Harnessing mRNA to Illuminate the Hidden World of Cells
MEETING ROOM 2
SCIROCCO
Parallel
–
MEETING ROOM 3
LIBECCIO
Parallel
–
10:00 | 11:30
POSTER AREA
–
Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
Single Molecule Biophysics
Chair
Paolo Bianchini (IIT)
Invited
Laura Finzi (USA)
Using in vitro single-molecule approaches to dissect fundamental cellular processes
Expand to read
Selected orals
Luca Buccolieri
The interplay of transcription factors to establish processive bacterial transcription
Alvaro Lanza
Measuring irreversibility in stochastic systems by categorizing single-molecule
displacements
Chia-Liang Cheng
From Single Cells to Multicellular Clusters: Molecular Signatures of Early Multicellularity in Saccharomyces cerevisiae
MEETING ROOM 2
SCIROCCO
Parallel
INFORMATION PROCESSING AND OPTIMISATION OF STRATEGIES IN LIFE
Chairs
Antonio Celani (ICTP)
Bill Bialek (Princeton)
Invited
Gautam Reddy (Princeton)
Phenotypic heterogeneity in lag reflects an evolutionarily stable bet-hedging strategy
Expand to read
Selected orals
Jack Featherstone
Spider-ant predator prey interaction as a stochastic trapping problem
Hugo Le Roy
Information-Theoretic Constraints on the Combinatorial Chemo-sensation of the Octopus
Hardik Rajpal
Information-Theoretic Emergence and the Physics of Biological Self-Organisation
Shiling Liang
Universal Physical Constraints on Biological Information Processing: A Nonlinear Response Framework
MEETING ROOM 3
LIBECCIO
Parallel
DEVELOPMENT AND MORPHOGENESIS
Chair
Pasquale Ciarletta MOX (Politecnico di Milano)
Invited
Giorgio Scita (IFOM, Milan)
Molecular Control of Tissue Fluidification Links Epithelial Mechanics to Anti-Tumor Immunity
Expand to read
Selected orals
Jacqueline Janssen
Decaying and expanding Erk gradients process memory of skeletal size during zebrafish fin regeneration
Wolfram Pönisch
The stochastic morphodynamics of cell state transitions
Philip Greulich
Emergent order in epithelial sheets by interplay of cell divisions and cell fate regulation
Konstantinos Andreadis
Pixels to Patterns: 3D Orientational Order and Topological Defects in Tissue Morphogenesis
11:30 | 12:00
COFFEE BREAK
12:00 | 13:30
POSTER AREA
–
Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
BIOLOGICAL FRONTIERS OF SOFT MATTER PHYSICS
Chair
Roberto di Leonardo (Rome)
Invited
Ramin Golestanian (Gottingen)
Non-reciprocal active matter
Expand to read
Selected orals
Luca Pellegrino
Reduction of bacterial colonization on buckling-induced wrinkled surfaces under fluid shear
Vladimir Rudyak
Does chemotaxis enhance target search by active Brownian particles?
Simone Benaglia
Atomic-Scale Dielectric and Structural Properties of Interfacial Water on Lipid Membranes
Giovanni Iaccucci
Controlling microalgae populations by phototactic memory
MEETING ROOM 2
SCIROCCO
Parallel
MECHANOBIOLOGY
Chair
Nils Gauthier (Milano)
Invited
Massimo Vassalli
Exploring the interplay between mechanics and mechanosensing
Expand to read
Selected orals
Judith Pineau
How do spheroids deform? Single-cell responses to tissue-scale geometry in breast cancer spheroids
Ondrej Kucera
Controlling Chiral Order in a Motor-Driven Active Cytoskeletal System
Diogo Pinto
Internal dissipation in a cell monolayer model mediates spontaneous hole formation
Henry De Belly
Long range mutual activation establishes Rho and Rac polarity during cell migration
MEETING ROOM 3
LIBECCIO
Parallel
DEVELOPMENT AND MORPHOGENESIS
Chair
Pasquale Ciarletta MOX (Politecnico di Milano)
Invited
Xavier Trepat (UPC)
Expand to read
Selected orals
Maddalena Staiano
Modeling cell fate decisions driven by prepatterns and geometry in organoid self-organization
David Oriola
An elastocapillary instability drives symmetry breaking in 3D multicellular aggregates
Marc Hennes
How bacterial aggregates mature: electrophysiology, mechanics, and morphogenesis
Emmy Blumenthal
Collective homeostasis in mean-field interacting systems
13:30 | 15:00
LUNCH
15:00 | 16:30
POSTER AREA
–
Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
CELLULAR BIOPHYSICS & SUPER-RESOLUTION MICROSCOPY
Chair
Valeria Rondelli (Milano)
Invited
Iva Tolic (Croatia)
One law linking genome and spindle across life
Expand to read
Selected orals
XiaoYu You
Nanodiamond–Berberine Nanocomplex Enhances Intracellular Delivery and Anticancer Activity in Melanoma Cells
Debashree Chakraborty
Deciphering “Endocytosis” vs “Direct Permeation” processes for Penetratin and Transportan 10 (TP10) peptides by Umbrella Sampling simulations.
Matthias Weiss
Anisotropic subdiffusion and nematic texture in the cytoplasm of living cells
Valeria Rondelli
Glycan-Induced Cellular Perturbation Controls Extracellular Vesicles–Membrane Interactions at the Nanoscale
MEETING ROOM 2
SCIROCCO
Parallel
INFECTION & IMMUNITY
Chair
Filippo Castiglione (CNR, Rome)
Invited
Thierry Mora
Diversity and dynamics of immune repertoires
Expand to read
Selected orals
Laura Collesano
Predicting the antigenic peptidome
Andrea Mazzolini
Inferring the dynamics of memory B cells and plasmablasts in healthy individuals
Arindam Ghosh
Decoding Immunotherapies at the Nanoscale
Anupama Jayaraman
Examining the Role of Antibody Feedback Loops in the Sequential Vaccination of Distinct Flaviviruses
Anna Burgstaller
3D synthetic tissues: Building an ex vivo training arena for immune cells
Juliana Ferreira-Strixino
Administration Route Effects on NanoBSA–Curcumin Photodynamic Therapy in Leishmania braziliensis
MEETING ROOM 3
LIBECCIO
Parallel
PROTEIN STRUCTURE & FUNCTION
Chair
Velia Minicozzi (Rome Tor Vergata)
Invited
Ruchi Anand (IIT Bombay)
Combatting Ribosomal Methylation Based Antibiotic Resistance: A war at the microscopic level
Expand to read
Selected orals
Alexey Ladokhin
Conformational Switching on Lipid Interfaces and Membrane Protein Insertion
Lilian Paty
Vimentin intermediate filaments promotes the self-assembly of actin filaments in vitro
Maria Li Lopez-Bautista
Non-equilibrium stabilization of proteins by the Hsp70 chaperone system
16:30 | 16:45
COFFEE BREAK
16:45 | 18:15
POSTER AREA
–
Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
CELLULAR BIOPHYSICS & SUPER-RESOLUTION MICROSCOPY
Chair
Valeria Rondelli (Milano)
Expand to read
Selected orals
Paolo Bianchini
Correlative AFM–fluorescence microscopy reveals multiscale mechanical and photooxidative pathways of hypericin-mediated membrane destabilization
Jhonatan Salgado
Peptidoglycan Dynamics Reveal Bacterial Super-Exponential Growth Under Nutrient and Antibiotic Perturbations
Eleni Papafilippou
Mechanical diversity of adhesion proteins underpins resilient epithelial junctions
Joseph Dijo Moonnukandathil
Glycan Atlassing: Nanoscale analysis of cell surface glycosylation enables functional tracing of cell state and reveals native glycoforms in situ.
Francesca Van Tartwijk
Cold adaptation of (sub)cellular organisation in the Antarctic spiny plunderfish Harpagifer antarcticus
MEETING ROOM 2
SCIROCCO
Parallel
INFECTION & IMMUNITY
Chair
Filippo Castiglione (CNR, Rome)
Expand to read
Selected orals
Daniel P. Newton
How the immune system learns to generalize via antibody feedback
Kaylie Hausknecht
A Dynamic Quorum Model of Treg-Mediated Peripheral Tolerance
Erika Aloi
Dissecting the role of HMGB1 in the dynamics of NF-κB inflammatory signaling pathway using quantitative imaging
Michael Lässig
Exponential proofreading: the kinetic mechanism of B cell immune response and cross-protection
Nadezhda Esenkova
Modelling autoimmune and autoinflammatory diseases: a case study of psoriasis.
Nazlican Yurekli
Breaking the Spatial Barrier: Single-Molecule Mapping of EGFR Glycosylation among CD4+ T Cell stimulation.
Limozin Laurent
Multiscale physics of immune cell engagers
MEETING ROOM 3
LIBECCIO
Parallel
BIOLOGICAL FRONTIERS OF SOFT MATTER PHYSICS
Chair
Roberto di Leonardo (Rome)
Expand to read
Selected orals
Pan Jiang
Emergent integer topological defect in confined smectic-like living liquid crystals
Yi Peng
Confinement Reduces Bacterial Surface Accumulation via Hydrodynamic Quadrupole Interactions
Akshit Aggarwal
Developing strategies to control the flows and densities in 3-D active isotropic fluids
Martin Kjøllesdal Johnsrud
Fluctuation dissipation relations for active field theories
Raphaël Jeanneret
Shedding light on micro-algae: phototaxis-induced collective phenomena
Nividha
Enzyme-Regulated Non-Thermal Fluctuations Enhance Ligand Diffusion and Receptor-Mediated Endocytosis
Swen Helstroffer
How Plant Pathogen Microswimmers Use pH Gradients: Active and Passive Mechanisms
Azam Gholami
Oxygen deficiency drives drastic pattern transition in algal bioconvection
18:15 | 19:30
WELCOME COCKTAIL
TUESDAY 30 JUNE
09:00 | 09:45
POSTER AREA
–
Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
Plenary
Toshio Ando
(Kanazawa University)
Directly observing structure and dynamics of protein molecules in action
MEETING ROOM 2
SCIROCCO
Parallel
–
MEETING ROOM 3
LIBECCIO
Parallel
–
09:45 | 11:15
POSTER AREA
–
Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
MECHANOBIOLOGY
Chair
Nils Gauthier (Milano)
Expand to read
Selected orals
Stefano Leporatti
Bio-Hybrid Atomic Force Microscopy: a Tool for Revealing Morpho-Mechanics of Cells and Biomimetic Substrates
Agustina Belen Fernandez Casafuz
Mechanobiology of mitochondria: interaction with the cytoskeleton and active forces
Cristina Scielzo
Mechanical forces drive adaptation and therapy resistance in Chronic Lymphocytic Leukemia cells
Baptiste Vauléon
Mechanics of the cortex:How does a polarised single cell shape itself?
Giovanni Buccioli
Quantitative Optical Microscopy Reveals Architecture-Dependent Mechano-Metabolic States in 3D Stem Cell Niches
Silvia Grigolon
Repeated extrinsic and anisotropic mechanical inputs promote C. elegans polarized adherens junction elongation
Jiayu Li
Flow‐induced Deformation and Apparent Rheology of Eukaryotic Cells in Microchannels
MEETING ROOM 2
SCIROCCO
Parallel
BIOLOGICAL NETWORKS AND COMPLEXITY
Chair
Irene Giardina (Rome)
Invited
Nikhta Fakhri (MIT)
Expand to read
Selected orals
Lisa Gennai
Partner determination from protein sequences using class information
Swarnavo Basu
Self-Organized Homogenization of Flow Networks
Ludovic Keiser
Embolism spreading in plants as a two-phase invasion process in a compliant vascular network
Macoto Kikuchi
Emergence of protein foldability from functional evolution in a lattice model
Tatjana Skrbic
Space-filling discrete helices
MEETING ROOM 3
LIBECCIO
Parallel
NEW OPTICAL TECHNIQUES
Chair
Cristiano Viappiani (Parma)
Invited
Sandrine Leveque Fort (U Paris Saclay)
Giuseppe Vicidomini (IIT Ge)
Photon-Resolved Laser-Scanning Microscopy with SPAD Arrays for Combined Imaging and Spectroscopy
Expand to read
Selected orals
Diego Sali
Chemical imaging and molecular spectroscopy: the definitive approach
Giuseppe Chirico
IN2SIGHT: a bioengineered chip for multiphoton imaging in vivo.
11:15 | 11:45
COFFEE BREAK
11:45 | 13:15
POSTER AREA
–
Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
MECHANOBIOLOGY
Chair
Nils Gauthier (Milano)
Expand to read
Selected orals
Berin Becic
Modeling the mechanosensitivity of endothelial alignment to weak shear flows
Gianmarco Spera
Active nematic on a viscoelastic substrate
Sindhu Muthukrishnan
Glassy dynamics in active epithelia emerge from an interplay of mechanochemical
feedback and crowding.
Giovanni Buccioli
A 3D microscaffold unmasks the mechanobiological basis of cancer multidrug resistance
Georgia Kefala
Microfluidics approach to study the role of mechano-chemical cues during vertebrate somite formation
Torben Sunkel
Motility-induced mixing transition in exponentially growing multicellular spheroids
Michela Pitto
Contractility Assessment of Gut Tissues from Hirschsprung and Primary PIPO: A Pilot Study
Isabelle Wielert
Differential active adhesion and a capillary instability drive global eversion and dissemination of bacterial colonies
Jen-Yu Lo
A general model for complex cell motility patterns induced by mechanosensitive bonds
MEETING ROOM 2
SCIROCCO
Parallel
BIOLOGICAL NETWORKS AND COMPLEXITY
Chair
Irene Giardina (Rome)
Expand to read
Selected orals
Daniel Maria Busiello
Thermodynamic Space of Chemical Reaction Networks
Milad Rahimi-Majd
Absorbing Markov Chains model the carbon dioxide diffusion in plant leaves
Nicolas Rocquelain
Form follows function: evolving a conformational switch in a lattice protein model
Kenji Okubo
Heterosis of fitness and phenotypic variance in the evolution of a diploid gene regulatory network
Philippe Bourianne
Transport of nutrients in symbiotic fungal networks
El Asri Jabir
Cilia beating coordination on airway epithelia : position and beating orientational correlations
MEETING ROOM 3
LIBECCIO
Parallel
ENERGY HARVESTING AND PROCESSING IN LIFE
Chair
Yihui Shen (UPenn)
Invited
Benedetta Mennucci (Pisa,Italy)
A Quantum Chemical Perspective of energy flow and photoprotection in photosystem II
Teuta Pilizota
The role of large concentration of impermeable ions in generation of membrane potential in Escherichia coli
Expand to read
Selected orals
Shen Yihui
Mitochondrial ATP generation is more proteome efficient than glycolysis
Junjie Liu
Mitochondrial power-efficiency trade-off in living cells
13:15 | 14:45
LUNCH
14:45 | 16:15
POSTER AREA
–
Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
SINGLE MOLECULE BIOPHYSICS
Chair
Paolo Bianchini (IIT)
Invited
Susanne Reinhardt (Germany)
Expand to read
Selected orals
Giselle Tan
Disulfide bond formation regulates vinculin recruitment in the R2 domain of Talin.
Antonio Patrón Castro
Flashing-ratchet model for the stepping dynamics of dimeric transport motors
Monica Marini
From DNA characterization to metrology: advanced strategies
Pedro J. de Pablo
Physical Virology with atomic force and fluorescence microscopies: seeing and
touching viruses
MEETING ROOM 2
SCIROCCO
Parallel
CELLULAR BIOPHYSICS & SUPER-RESOLUTION MICROSCOPY
Chair
Valeria Rondelli (Milano)
Expand to read
Selected orals
Ranieri Bizzarri
Intranuclear Dynamics And Mesoscale Assembly Of Polyhomeotic 2 Chromatin Remodeler
Anne-Pia Marty
An optical microscopy and multi-omics approach to subcellular cold adaptation in Antarctic fish
Oriol Gallego
Physical chemistry and evolution of exocytosis in the Saccharomyces genus: lessons from advanced microscopy
Benjamin Friedrich
Sarcomere self-assembly in muscle
Mariateresa Panarelli
Targeting connexin hemichannels in glioblastoma with the abEC1.1 monoclonal antibody
Louison Blivet-Bailly
Vascular Endothelial Integration of Multiple Biophysical Stimuli
MEETING ROOM 3
LIBECCIO
Parallel
QUANTITATIVE CELL PHYSIOLOGY
Chairs
Marco Cosentino Lagomarsino (IFOM)
Invited
Ariel Amir (Israel)
Extracting biological insights from bacterial single-cell data
Expand to read
Selected orals
Ben Shenhar
Maximal human lifespan in light of a mechanistic model of aging
Giorgio Tallarico
Coordinated control of translation and protein turnover drives yeast growth
Kuheli Biswas
Cell Size Regulation Strategies from Bacteria to Mammalian Cells
Andrea Iglesias-Ramas
Bioelectric regulation of epithelial tissue organization
Miriam Schnitzerlein
How resident macrophages sample tissues: functional state analysis and protrusion behaviour
Lucas Le Nagard
Metabolic feedback during bacterial fermentation is a motility brake
16:15 | 16:45
COFFEE BREAK
16:45 | 18:15
POSTER AREA
–
Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
INFORMATION PROCESSING AND OPTIMISATION OF STRATEGIES IN LIFE
Chairs
Antonio Celani (ICTP)
Bill Bialek (Princeton)
Invited
Agnese Seminara (Genoa)
Noise enhances odor source localization
Expand to read
Selected orals
Shiau-Mei Lin
Pa2Pd: Transformer-Based Reconstruction of Distal Coronary Pressure from Resting Aortic Waveforms for Wire-Free Functional Stenosis Assessment
Pierpaolo Bruscolini
Biotechnological applications of 1D exactly solvable models
Michael Lässig
Adaptive ratchets and the evolution of complex information processing
Benjamin Friedrich Information theory of chemotactic agents using both spatial and temporal gradient sensing
Enrico Maiorino
Integrating local and global cues for optimal source finding
without gradients
Larbi Touijer
Generative Adversarial Networks for Nuclear Label Free to Fluorescence Prediction with Chromatin Level Evaluation
MEETING ROOM 2
SCIROCCO
Parallel
CELLULAR BIOPHYSICS & SUPER-RESOLUTION MICROSCOPY
Chair
Valeria Rondelli (Milano)
Invited
Gregory Giannone (Bordeaux)
Expand to read
Selected orals
Blanca Bruschi
Nanoscale characterization of X-Ray-induced chromatin alterations in neuroblastoma cells
Luca Lanzanò
Spot-Variation Fluorescence Correlation Spectroscopy (FCS) on an Image Scanning Microscope (ISM)
Gabriele S Kaminski Schierle
Alpha-Synuclein Facilitates Dopamine Release in a Calcium- and Phosphorylation-Dependent Manner
Martina De Felice
Super-Resolution Imaging of radiation-induced DNA Damage and Cytoskeletal Remodelling
MEETING ROOM 3
LIBECCIO
Parallel
SINGLE MOLECULE BIOPHYSICS
Chair
Paolo Bianchini (IIT)
Invited
Davide Mazza (Italy)
p53 Dynamics at multiple scales: from single-molecule to systems biology
Expand to read
Selected orals
Daniela Moretti
Supercoiling DNA with a free end
Kamila Sofinska
Nanospectroscopic Insights into Tau Protein Fibrillization and Its Modulation by Small‑Molecule Inhibitors
WEDNESDAY 1 JULY
09:00 | 09:45
POSTER AREA
–
Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
Plenary
Julia Yeomans (Oxford)
Modelling Epithelial Tissues as Active Materials
MEETING ROOM 2
SCIROCCO
Parallel
–
MEETING ROOM 3
LIBECCIO
Parallel
–
09:45 | 11:15
POSTER AREA
–
Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
MECHANOBIOLOGY
Chair
Nils Gauthier (Milano)
Invited
Pere Roca-Cusachs (Barcelona)
Mechanical regulation of nucleocytoplasmic transport and nuclear envelope tension
Expand to read
Selected orals
Natalie Huhn
Traction forces facilitate maximal motility of immune cells after division
Andrea Lagomarsino
Cell mechanics and mechanotrasduction is altered in ADLD pathology. Insights from AFM and Brillouin Analysis
Amaris Guevara Garcia
Role of bi-directional force coupling on the spatial regulation and activation of integrin nanoclusters inside focal adhesions
Ana Raffaelli
Basement membrane mechanics drives patterned response to developmental signalling
MEETING ROOM 2
SCIROCCO
Parallel
PHASE SEPARATION, CROWDING AND CONDENSATES IN BIOLOGY
Chair
Antonio José da Costa Filho (Sao Paolo, Brazil)
Invited
Paolo de Los Rios (EPFL, Lausanne)
Phase boundaries promote chemical reactions through localized fluxes
Expand to read
Selected orals
Trevor GrandPre
Principles of Client Enrichment in Multicomponent Biomolecular Condensates
Xiakun Chu
Chromatin fluctuations and transcriptional condensates orchestrate the enhancer-promoter communication in 3D genome
Max Kerr Winter
The role of lipid emulsion condensates in carbon transport through mycorrhizal fungal networks
Adrielle Theresa Cusi
Actin Dynamics Suppress Liquid-liquid Phase-Separation
Tommaso Inzani
Polymer conformational entropy as the driver of RNA-peptide biomolecular condensation
MEETING ROOM 3
LIBECCIO
Parallel
CHROMOSOMES AND NUCLEI: GENE REGULATION, ORGANIZATION AND DYNAMICS
Chair
Giada Forte
Invited
Mario Nicodemi (Naples)
Phase transitions in the nucleus of cells shape chromosome 3D architecture and functions
Expand to read
Selected orals
Alberto Sassi
Titration and Cooperativity Control DNA Replication Timing in Bacteria
Yagyik Goswami
Epigenomics-informed modeling of actively driven chromatin reorganisation in cell state transitions
Rakesh Das
Theory of DNA-end tethering via break-induced DNA-protein condensation
Manghi Manoel
How chromatin dynamics is modified by transcription bursts and cell cycle?
11:15 | 11:45
COFFEE BREAK
11:45 | 13:15
POSTER AREA
–
Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
ORIGINS OF LIVING MATTER
Chair
Ranieri Bizzarri (Pisa)
Invited
Nick Lane (UCL)
Philippe Nghe (EPSCI Paris)
Expand to read
Selected orals
Simone Codispoti
RNA-Peptide World: prebiotic peptides and libraries driving ancestral ribosome coacervation
Sara Drechsler
CaCO3 precipitation in giant unilamellar vesicles triggered by fusion with Ca2+-filled large unilamellar vesicles
MEETING ROOM 2
SCIROCCO
Parallel
PHASE SEPARATION, CROWDING AND CONDENSATES IN BIOLOGY
Chair
Expand to read
Selected orals
Martin Kjøllesdal Johnsrud
Non-reciprocal interactions between condensates in chemically active mixtures
Andrea Gamba
Enzyme-driven phase separation
Jakob Metson
Enzymes can activate and mobilize dense biomolecular condensates across scales
Ignacio Sanchez Burgos
Interplay between Local Diffusion, Concentration, and Inter-Protein Alignment Promotes Cross-β-Sheet Transitions at Condensate Interfaces
Midhun Puthumana Melepattu
From Single-Cell Crowding to Colonial Gradients: A Multiscale View of CMD Regulation
Maximilian Winkler
Membrane viscosity and line tension in phase-separated pore-spanning plasma membranes
Alexander Chervanyov
Kinetic model of static and dynamic flocking in a system of self-propelled agents
INFECTION & IMMUNITY
Chair
Filippo Castiglione (CNR, Rome)
Invited
Arup Chakraborty
How the Humoral Immune System Learns
MEETING ROOM 3
LIBECCIO
Parallel
CHROMOSOMES AND NUCLEI: GENE REGULATION, ORGANIZATION AND DYNAMICS
Chair
Enrico Skoruppa
Expand to read
Selected orals
Nessim Louafi
Cohesin loop extrusion creates rare, long-lived encounters supporting long-range regulation
Roberto Di Leonardo
Photoreceptors as Optical Interfaces for Synthetic Genetic Circuits
Michael Chiang
A transcription-driven microgel network poised near the sol-gel transition
Bogdan Slavov
Stochastic kinetics of enhancer-promoter contacts mediated by loop extrusion
Carolina Palombo
Polycatenane assembly with Topo II in toroidal confinement
Oliver Henrich
oxDNA3 — Introducing sequence-specific curvature and elasticity into a coarse-grained DNA model
Beatrice Ruzzante
Single-Molecule Tracking of p53 at DNA-Damage Foci
Samuel Zambrano
Inflammatory signals perturb p53 oscillatory dynamics hampering DNA repair.
Giorgio Bini
Deep Learning for RNA–RNA Interaction Prediction
13:15 | 14:45
LUNCH
14:45 | 16:15
POSTER AREA
–
Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
MECHANOBIOLOGY
Chair
Nils Gauthier (Milano)
Expand to read
Selected orals
Oriol Nos
Intracellular viscoelasticity and membrane force dynamics quantified with optical tweezers
Raviv Dharan
Intracellular pressure and membrane excess area control tension propagation in crumpled cell membranes
Monika Szczepanek-Dulska
Role of substrate stiffness in modulating the effects of radiation on brain cells
Margherita De Marzio
Understanding the Role of Surface Curvature on Epithelial Plasticity
Katja Zieske
A Lab-on-a-Chip Platform for Controlled Mechanical Perturbations of Biopolymer Networks and Cellular Systems
Katarzyna Pogoda
Extracellular Matrix Viscoelasticity Modulates Glioblastoma Migration and Reduces Sensitivity to Temozolomide
Francesca Cecilia Lauta
Biophysical modulation of macrophages behaviour in 3D microenvironment
Eloïse Epaud-Halouchery
Mechanical properties of the actin cortex
MEETING ROOM 2
SCIROCCO
Parallel
CHROMOSOMES AND NUCLEI: GENE REGULATION, ORGANIZATION AND DYNAMICS
Chair
Oliver Henrich
Invited
Thomas Gregor (Princeton)
Spatially correlated fluctuations govern relative chromatin motion
Expand to read
Selected orals
Michael Wilkinson
Ambigrammatic Viruses
Manish Yadav
Physical Mechanisms Underlying Nucleosome Retention in Spermiogenesis
Giada Forte
A Unified 3D Model of DNA Replication Dynamics Across Bacteria and Eukaryotes
Alberto Raiola
Phase behaviour and epigenetic memory in magnetic polymer models for chromatin
Guglielmo Grillo
Organisation and dynamics of individual DNA segments in topologically complex genomes
Enrico Skoruppa
Exploring the Mechanical Genome: From Base-Pair–Level Analytics to Systematic Coarse-Graining
Giorgio Ravanelli
Decoupling between activation time and steady-state level in input-output responses
Hawraa Zbeeb
Epigenetic remodeling of histone modifications and chromatin architecture during neuroblastoma cell retro-differentiation
MEETING ROOM 3
LIBECCIO
Parallel
BIOLOGICAL NETWORKS AND COMPLEXITY
Chair
Irene Giardina (Rome)
Invited
Yuhai Tu (Flatiron Inst.)
Nonequilibrium thermodynamics in biochemical networks: Towards answering Schrödinger’s question
Expand to read
Selected orals
Roger Rubio-Sanchez
Lipid membrane biophysics and bioengineering using DNA nanostructures for bottom-up membrane signalling
Jonathan Fiorentino
Dissecting protein representations through the Information Imbalance
Paul Sitoleux
Maximum Entropy models for scRNA-seq data
16:15 | 16:45
COFFEE BREAK
16:45 | 17:30
POSTER AREA
–
Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
Plenary
Iupap Young Scientist &
Early Career Awards
IUPAP Early Career Scientist Prize 2025
Viola Introini (MPI for the Science of Light, Erlangen, Germany)
Alexander Mietke
MEETING ROOM 2
SCIROCCO
Parallel
–
MEETING ROOM 3
LIBECCIO
Parallel
–
17:30 | 18:15
POSTER AREA
–
Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
Plenary
IUPAP Medal
Physics of Life 2026:
Uri Alon
MEETING ROOM 2
SCIROCCO
Parallel
–
MEETING ROOM 3
LIBECCIO
Parallel
–
19:30 | 23:00
SOCIAL DINNER AT VILLA LO ZERBINO
THURSDAY 2 JULY
09:00 | 09:45
POSTER SESSION
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Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
Plenary
Amos Maritan
(Padova)
Optimization, Scaling, and Dynamics from Single Plants to Forests
MEETING ROOM 2
SCIROCCO
Parallel
–
MEETING ROOM 3
LIBECCIO
Parallel
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09:45 | 11:15
POSTER SESSION
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Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
QUANTITATIVE CELL PHYSIOLOGY
Chairs
Marco Cosentino Lagomarsino (IFOM)
Invited
Luca Ciandrini
A bottom-up view of the growth laws: ribosome allocation, interference, and what counts as “active”
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Selected orals
Vahid Shahrezaei
Cellular resource allocation in budding yeast beyond steady state
Leon Seeger
From bacterial growth laws to detecting drug action mechanisms
Gabriela Petrungaro
Function-specific epistasis shapes evolutionary trajectories towards antibiotic resistance
Michael Sheinman
Modeling global transcription dynamics within the cell cycle using scRNA-seq data
MEETING ROOM 2
SCIROCCO
Parallel
PROTEIN STRUCTURE & FUNCTION
Chair
Velia Minicozzi (Rome Tor Vergata)
Invited
Nunilo Cremades (University of Zaragoza, Spain)
Structural Evolution of Protein Network Architecture in Biomolecular Condensates: Implications for Function and Disease
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Selected orals
Cristina Cantarutti
Exploring the effect of mutations and stabilizers on TTR conformational landscape through HDX NMR
Ilpo Vattulainen
How do nanodiscs and bicelles modulate the conformational distribution of membrane receptors?
Daniel Harries
Self-crowding reshapes protein structure and interactions beyond excluded volume
Matilde Pattanaro
Mapping and engineering binding affinity and specificity in antibodies
Rafayel Petrosyan
Orb2 amyloid core stability dependence on the number of monomers
MEETING ROOM 3
LIBECCIO
Parallel
BIOLOGICAL FRONTIERS OF SOFT METTER PHYSICS
Chair
Roberto di Leonardo (Rome)
Invited
Zvonimir Dogic (UCSB)
Active assembly and non-reciprocal dynamics of elastic membranes Selected orals
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Selected orals
Mark Besse
Emergent memory and environmental sensing in models of motile cells
Paul Pineau
Collective dynamics of trail-interacting particles.
Kristian Müller-Nedebock
Modelling mutual interplay of organelle transport and the dynamic re-organisation of cytoskeletal networks
Dongliang Zhang
The energy cost to construct a spindle
Adriano Caliari
Engineering superselectivity in a synthetic endocytosis model
Mauro Manno
The physico-chemical landscape of extracellular vesicles: implications for their engineering and function
11:15 | 11:45
COFFEE BREAK
11:45 | 13:15
POSTER SESSION
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Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
THE BRAIN AND NEURAL NETWORKS
Chair
Sebino Stramaglia (Bari)
Invited
Daniele Marinazzo (Ghent, Belgium)
Collective behavior in neuroscience through the eyes of statistical physics
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Selected orals
Yoshiaki Horiike
Irreversible dynamics of the human brain and its structural origin
Alessandro Fiasconaro
Effects of inhibition and synaptic location on synchronization in a realistic model of CA1 pyramidal neurons.
Hardik Rajpal
Synergistic Information Mediates Long-Range Correlations in Visual Cortex Near Criticality
Giulia Tomagra
From Quantum Diamonds to Neurobiology: Mapping Electrical and Thermal Signals in Neuronal Networks
MEETING ROOM 2
SCIROCCO
Parallel
PROTEIN STRUCTURE & FUNCTION
Chair
Velia Minicozzi (Rome Tor Vergata)
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Selected orals
Thomas Tarenzi
Fuzzy interactions shape the conformational landscape of histone H3 to direct PTM catalysis
Breanna Voss
Identification of Post-Translational Modifications on Lysine Amino Acids with Computational Methods
Simone Aureli
Free-Energy Landscapes Reveal Ligand-Controlled Access to Signaling States in GPCRs
Yessica Roque Diaz
Structural Dynamics of Fibrin Polymerization under Controlled Shear: A Microfluidic Approach
Shilpi Laha
Tunable Conformational Equilibria in an HMG Protein Couples DNA Binding-Bending Modes with Phase Separation Propensity
Francesco Rinaldi
Molecular determinants of the BRC Repeats – RAD51 recognition
MEETING ROOM 3
LIBECCIO
Parallel
BIOLOGICAL FRONTIERS OF SOFT MATTER PHYSICS
Chair
Roberto di Leonardo (Rome)
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Selected orals
Pietro Sillano
MesoMem: A mesoscale membrane model based on an additive potential
Raffaele Mendozza
Soft Glassy Rheology as a model for cytoskeletal mechanics
Paulo Casagrande Godolphim
Parameter degeneracy in the vertex model for tissues
Carlo Altucci
Innovative nanomaterials for biomedical applications
Nicola Pellicciotta
Internal stress drives ferromagnetic-like ordering in networks of proliferating bacteria
Thea Kristersdotter
Sponge Phase Lipid Nanoparticles for Biomolecular Delivery: Insights into Lipid Exchange, Biomembrane Interactions and Cellular Uptake
Davide Breoni
Interplay of activity and topology in active polymers
13:15 | 14:45
LUNCH
14:45 | 16:15
POSTER SESSION
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Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
PHASE SEPARATION, CROWDING AND CONDENSATES IN BIOLOGY
Chair
Invited
Lorenzo di Michele (Cambridge)
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Selected orals
Nicola Galvanetto
Material properties of biomolecular condensates emerge from the dynamics of single molecules
Giuliano Migliorini
Diffusion and enzymatic reactions in solutions crowded by the branched polymer dextran
Andres Tejedor Reyes
Deciphering the Sequence-Encoded Grammar of RNA Condensationsvia Coarse-Grained Modeling
Miljan Dašic
Multi-Scale Modeling of Metabolic Pathways in Crowded Environments
Michele Monti
RNA as modulator of protein physical state and cellular processes.
MEETING ROOM 2
SCIROCCO
Parallel
PROTEIN STRUCTURE & FUNCTION
Chair
Velia Minicozzi (Rome Tor Vergata)
Expand to read
Selected orals
Fausta Desantis
Pathogenic binding hindrance in a misfolded antibody light chain: an in silico approach to design an antagonist peptide
Walter Rocchia
NextGenPB: Fast, accurate Poisson–Boltzmann electrostatics for biomolecular surfaces
Soham Mukherjee
Fate of Knotted Proteins During Directed Degradation and Constrained Folding: Insights from Biochemical and Single-Molecule Force Spectroscopy
Matteo Piscitelli
Structural Evolution of Physisorbed Antibody Monolayers on Gold Revealed by PM-IRRAS and 2D Correlation Spectroscopy
Antonio Trovato
Entangled motifs generate energetic frustration in good-folding sequences within lattice protein models.
ECOLOGY AND EVOLUTION OF COMMUNITIES
Chair
Diana Fusco (Cambridge)
Expand to read
Selected orals
Davide Bernardi
Species vulnerability and coexistence in spatially-extended ecosystems
Stefania Melillo
Experimental evidence of male-male interaction in laboratory swarms of Anopheles gambiae mosquitoes
Rahul Mallikarjun
Ecology of extracellular decomposition
William Shoemaker
Investigating the macroecology of sojourn trajectories in the human gut microbiome
MEETING ROOM 3
LIBECCIO
Parallel
NEW OPTICAL TECHNIQUES
Chair
Cristiano Viappiani (Parma)
Invited
Vahid Sandoghdar (Erlangen Germany)
On sensitive detection of viruses, extracellular vesicles and proteins
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Selected orals
Silvia Caponi
Brillouin and Raman Microscopy of Breast tumor Spheroids On-a-Chip
Letizia Marchesi
Label-free 3D imaging of individual pollen grains by light diffractometry using cavitation microstreaming
Nicolo Incardona
Label-free observation of biological samples through polarization Mueller matrix microscopy
Concetta Santangelo
Investigation of Lipid Membrane Interactions with Fluorescence and Bright-Field Differential Dynamic Microscopy
Giacomo Donini
Driving the bacterial flagellar motor with light
Blanca Bruschi
The role of spectral-spatial crosstalk in Brillouin Microscopy
Maria Laura Sforza
Plasmonic Gold Nanorods Array for Label Free Optical Biosensing
16:15 | 16:45
COFFEE BREAK
16:45 | 18:15
POSTER SESSION
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Poster session
MEETING ROOM 1
MAESTRALE
Plenary&Parallel
PHASE SEPARATION, CROWDING AND CONDENSATES IN BIOLOGY
Chair
Expand to read
Selected orals
Ekaterina Krasnopeeva
Cytoplasm condensation in de-energised Escherichia coli cells.
Johannes Keegstra
Spontaneous switching in a protein signalling array reveals near-critical cooperativity
Loredana Casalis
Multiscale Regulation of Liquid–Liquid Phase Separation in Lipid Membranes by Cholesterol
Juliette Bucci
Mimicking cellular energy storage with phase separated ATP-responsive membraneless compartments.
Andrei-Alexandru Paraschiv
Non-equilibrium effects in the formation of multiphasic RNA condensates
Yutong Fu
Coalescence and dynamics in protein condensates out of equilibrium
MEETING ROOM 2
SCIROCCO
Parallel
ECOLOGY AND EVOLUTION OF COMMUNITIES
Chair
Diana Fusco (Cambridge)
Invited
Martina Dal Bello (Yale University)
Nutrient availability shapes the diversity and structure of microbial communities
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Selected orals
Jacopo Marchi
Stable coexistence and transport of lytic phage infections with migrating bacterial hosts
Berenike Maier
Predictability of horizontal gene transfer in changing environments
Federico Mazzei
ChAMBRe: an European Hub for Advanced Bioaerosol Research
Sergei Maslov
Crossfeeding Dynamics in Energy-Limited and Auxotrophic Microbial Communities
MEETING ROOM 3
LIBECCIO
Parallel
BIOLOGICAL FRONTIERS OF SOFT MATTER PHYSICS
Chair
Roberto di Leonardo (Rome)
Expand to read
Selected orals
Luca Tubiana
Biologically inspired topological soft materials: from the kinetoplast DNA to circular polycatenanes
Julia Blandine Bassila
Number And Compositional Asymmetry Influence Interleaflet Coupling And Phase Transitions Of Lipid Membranes
Dan Shafir
Impact of Material Turnover on Diffusion in Bacterial Cell Walls: A Random Walk on a Dynamic Percolation Network
Sebastian W. Krauss
Microfluidic Micropipettes: A Chip-Based Platform for Membrane Mechanics at Scale
Antonella Battisti
Unconventional biosensing platforms for the label-free monitoring of plant metabolic markers
Andrea Perna
A minimal mechanical framework for elongation and exploratory dynamics in Lacrymaria
18:15 | 20:00
CITY TOUR
FRIDAY 3 JULY
09:00 | 09:45
POSTER AREA
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MEETING ROOM 1
MAESTRALE
Plenary&Parallel
Plenary
Athanassia Athanassiou
Emerging Materials Platforms from Circular Bioresources for Advanced Wound Healing
MEETING ROOM 2
SCIROCCO
Parallel
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MEETING ROOM 3
LIBECCIO
Parallel
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09:45 | 11:15
POSTER AREA
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MEETING ROOM 1
MAESTRALE
Plenary&Parallel
THE BRAIN AND NEURAL NETWORKS
Chair
Sebino Stramaglia (Bari)
Invited
Martijn van den Heuvel (UV, The Netherlands)
Expand to read
Selected orals
Chiara Bartoli
Brillouin Microscopy on ALS-related protein aggregates in living cells
Giovanna Cimaglia
Spectral Characterization Of BODIPY-based Fluorophore BT1 For Detection Of Alzheimer’s Disease
Luca Tubiana
The emergence of memory in biased random walks on networks: metaplasticity and shared memories
MEETING ROOM 2
SCIROCCO
Parallel
PHYSICAL ASPECTS OF STEM CELLS AND CANCER
Chair
Michele Caselle (Torino)
Invited
Edouard Hannezo
Mechanical models of stem cell fate choices
Antonio Scialdone
From Genomic Architecture to Cell Fate: The Logic of Olfactory Receptor Choice
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Selected orals
Filippo Valle
Multi-Omics Topic Modeling for Cancer Subtypes Classification
Hossein Nemati
Mean-Field Models for Cell Competition in Cancer Metastasis
Francesco Saverio Rotondi
Inheritance entropy quantifies epigenetic regulation of cell-cycle exit in human bone marrow stromal cells
Marco Malferrari
Acute Myeloid Leukemia Cell Motility Under Hypoxic Oxygen Gradients
MEETING ROOM 3
LIBECCIO
Parallel
ECOLOGY AND EVOLUTION OF COMMUNITIES
Chair
Diana Fusco (Cambridge)
Invited
Anne-Florence Bitbol
Impact of complex spatial population structures on biological evolution
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Selected orals
Thibaut Arnoulx de Pirey
Generic scale invariance in complex model ecosystems
Tommaso Bellini
Synthetic evolution of molecular ecosystems
Johannes Keegstra
To swim or not to swim: quantifying the energetic cost of bacterial foraging using nanocalorimetry.
Tommaso Redaelli
Auxotrophic microbial communty dynamics in fragmented environments
11:15 | 11:45
COFFEE BREAK
11:45 | 12:30
POSTER AREA
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MEETING ROOM 1
MAESTRALE
Plenary&Parallel
Plenary
RISING STARS and MEDAL
MEETING ROOM 2
SCIROCCO
Parallel
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MEETING ROOM 3
LIBECCIO
Parallel
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12:30
POSTER AREA
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MEETING ROOM 1
MAESTRALE
Plenary&Parallel
CLOSING REMARKS
AND FAREWELL
MEETING ROOM 2
SCIROCCO
Parallel
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MEETING ROOM 3
LIBECCIO
Parallel
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